Rottlerin
APC-942
Rottlerin
Cat. No.
APC-942
CAS No.
82-08-6
MF
C30H28O8
MW
516.5
Rottlerin, a natural product purified from Mallotus Philippinensis, is a specific PKC inhibitor.
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Technical Data
Description
Storage and Shipping
References
Product Name
CAS No.
82-08-6
MF
C30H28O8
MW
516.5
Specification
98%
Research Area
Anti-tumor and antiviral
Description
Rottlerin, a natural product purified from Mallotus Philippinensis, is a specific PKC inhibitor. Packing: 10mg, 20mg, 50mg, 100mg, 500mg, 1g, 5g, 10g Availability: In stock
Storage and Shipping
Store under frozen or refrigerated conditions, keep away from strong light and heat.
References
[1]. Gschwendt M, et al. Rottlerin, a novel protein kinase inhibitor. Biochem Biophys Res Commun. 1994 Feb 28;199(1):93-8.
[2]. Valacchi G, et al. Rottlerin exhibits antiangiogenic effects in vitro. Chem Biol Drug Des. 2011 Jun;77(6):460-70.
[3]. Minzhao Huang, et al. Rottlerin suppresses growth of human pancreatic tumors in nude mice, and pancreatic cancer cells isolated from KrasG12D mice. Cancer Letters 353 (2014) 32-40.
[4]. María Rosa López-Huertas, et al. Protein kinase Ctheta is a specific target for inhibition of the HIV type 1 replication in CD4+ T lymphocytes. J Biol Chem. 2011 Aug 5;286(31):27363-77.
[5]. Zoé Lama, et al. Kinase inhibitors tyrphostin 9 and rottlerin block early steps of rabies virus cycle. Antiviral Res. 2019 Aug;168:51-60.
Disclaimer
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